Oral Cancer Screening Technology

Dr. Sattelberg and his team members offer the latest technology in oral cancer screening. There are many risk factors such as lifestyle, environment, genetics and other conditions that may increase a persons risk of developing oral cancer. Our patient’s health is extremely important to us and we offer several different technologies that allow us to properly detect oral cancer. 

Velscope Enhanced Oral Assessment 

Velscope centers on a wireless, handheld scope that uses natural tissue fluorescence to enhance the way clinicians visualize oral mucosal abnormalities that might not be apparent or even visible to the naked eye. This technology is recognized by the World Health Organization and is the world’s most widely used adjunctive device for the enhanced visualization of oral mucosal abnormalities, such as oral cancer or pre-malignant dysplasia.

Traditional oral mucosal examination tools rely on reflected light to visualize the oral cavity. VELscope® Vx uses tissue fluorescence rather than reflectance. Natural tissue fluorescence is caused by “fluorophores” that, when excited by light of an appropriate wavelength (e.g. blue), will emit their own light at a longer wavelength (e.g. green). The resulting fluorescence may reveal information about cellular, structural, and/or metabolic activity changes that are often directly related to disease processes occurring inside the tissue.

Identafi Oral Cancer Screening System

The deep penetrating power of the Identafi® multiple wavelengths will enhance the early detection of mucosal abnormalities that may be cancerous. The new Identafi® uses the Identafi® Multi-Spectral Fluorescence and Reflectance technology to enhance visualization of mucosal abnormalities such as oral cancer or premalignant dysplasia that may not be apparent to the naked eye. But unlike other fluorescence technologies and dye systems, the Identafi® is Multi-Spectral with three distinct color wavelengths, making it easier to distinguish lesion morphology and vasculature aiding the dental professional in determining next steps.

The Identafi® uses white, violet and amber wavelengths of light to excite oral tissue in distinct and unique ways. As a result, biochemical changes can be monitored with fluorescence, while morphological changes can be monitored with reflectance. The combined system of fluorescence and reflectance uses the body’s natural tissue properties as an adjunctive tool for oral mucosal examination. Conventional examination of tissue is performed using a highly concentrated White light. Wearing reusable Identafi® filtered eyewear to enhance visual effects and allow transmission of reflected light, the health professional then switches to Violet for a second observation. The clinician’s photosensitive glasses block the violet excitation light and allow the observance of the tissues natural fluorescence. Violet light enhances normal tissue’s natural fluorescence; however, suspicious tissue appears dark because of its loss of fluorescence. When suspect abnormalities are present the selector is switched to Amber light, which enhances normal tissue’s reflectance properties so the clinician may directly observe the difference between normal and abnormal tissue’s vasculature. This independent view of vascular architecture may assist in the assessment of confounders when screening for oral cancer. Studies indicate abnormal tissue has a diffuse vasculature, where normal tissue vasculature is clearly defined. The combination of all three Multi-Spectral wavelengths provides the clinician with more visual information, improved results over direct visual exam alone and increased confidence for recommending biopsies.